Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Seek affordable acreage in McLean County, Western Kentucky, with Calhoun as its county seat. This tranquil region, home to just under 9,500 residents, features rolling farmland and river access, presenting an excellent opportunity for those desiring a peaceful rural lifestyle or agricultural investment.