Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Embrace the great outdoors in McCreary County, Eastern Kentucky, with Whitley City as its county seat. This county of approximately 17,000 residents is a gateway to Daniel Boone National Forest, offering unparalleled opportunities for hunting, hiking, and building a secluded cabin or homestead.