Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Grayson County is a Central Kentucky county centered on Leitchfield. Rough River Lake, affordable rural acreage, and a growing small-town economy attract land buyers seeking value and outdoor recreation.