Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington. Uncover prime land in Graves County, a key part of Kentucky's Western region with Mayfield as its county seat. Supporting a population of 37,266, this county is known for its productive farmland and strong community spirit, making it an attractive destination for agricultural pursuits and establishing a self-sufficient homestead.