Barren County is a South Central Kentucky agricultural hub centered on Glasgow. Mammoth Cave National Park borders the county, and the area offers some of the most affordable productive farmland in the state. Fayette County is home to Lexington, Kentucky's second-largest city and the heart of the Bluegrass Region. Known for horse farms, rolling pastures, and strong land values, Fayette County offers urban amenities alongside agricultural heritage. County seat: Lexington.